Real Betis vs Vitoria Guimaraes Prediction, lineups, betting tips & odds

The hosts are undefeated against Vitoria Guimaraes across all competitions.
Real Betis are all set to host Vitoria Guimaraes in the first leg of the UEFA Europa Conference League 2024-25 round of 16 contest. They were in the 15th spot when the league phase ended, which resulted in them playing in the playoffs phase. The visitors on the other hand had a fantastic run in the league phase finishing in second place.
Real Betis will be at home and will be full of confidence. They defeated Gent in the playoffs phase to seal the round of 16 berth. They also defeated Real Madrid in their last league (LaLiga) fixture. They will look to continue their form going further. The hosts will look to attack and score some goals, which will help them take an advantage.
Till now, Vitoria Guimaraes are having a good run in the UEFA Conference League, but their upcoming clash against Real Betis is going to be a tough affair. The LaLiga side are looking in good shape from their last few games and on top of that it will be their home ground. Guimaraes will have to defend well and try to score a goal or two here.
Kick-off:
- Location: Seville, Spain
- Stadium: Benito Villamarin Stadium
- Date: Thursday, March 6
- Kick-off Time: 23:15 IST/ 17:45 GMT/ 12:45 ET/ 09:45 PT
- Referee: TBD
- VAR: In use
Form:
Real Betis: W-W-L-W-W
Vitoria Guimaraes: W-D-D-D-W
Players to Watch
Isco (Real Betis)
The Spanish midfielder is very consistent on the field for Real Betis. This is a big positive for the hosts as they are now going to compete in the UEFA Conference League round of 16 against Vitoria Guimaraes. Isco knows how to take control of the midfield and build plays for the attacking front. He surely is very capable of scoring goals as well.
Tiago Silva (Vitoria Guimaraes)
The Portuguese midfielder will be playing a big role in the absence of Vitoria’s main forward Gustavo Silva. Tiago Silva has scored a couple of goals for his side in the UECL this season. He can surely help the attacking front by timing his passes.
Match Facts
- This will be the third meeting between them across all competitions.
- Vitoria Guimaraes are undefeated in their last five matches in all competitions.
- Real Betis are on a two-match winning streak.
Real Betis vs Vitoria Guimaraes: Betting Tips and Odds
- Real Betis to win @13/20 Bet Goodwin
- Goals over 2.5 @6/5 Betfair Sportsbook
- Antony to score @15/2 bet365
Injury and Team News
Marc Roca, William Carvalho and three other squad members have injuries and will not be a part of Real Betis.
Vitoria Guimaraes will be without the services of Gustavo Silva and Bruno Gasparas as they are injured.
Head-to-Head
Total matches: 2
Real Betis won: 2
Vitoria Guimaraes won: 0
Draws: 0
Predicted Lineups
Real Betis predicted lineup (4-2-3-1)
Adrian (GK); Bakambu, Bartra, Llorente, Ricardo Rodriguez; Cardoso, Altimira; Antony, Isco, Jesus Rodriguez; Hernandez
Vitoria Guimaraes predicted lineup (4-2-3-1)
Varela (GK); Maga, Borevkovic, Oliveira, Teixeira Mendes; Silva, Handel; Arcanjo, Joao Mendes, Felix; Oliveira
Match Prediction
Real Betis are on a great run as they have come up with some good performances against the top teams. The hosts will be looking to continue their winning run and might defeat Vitoria Guimaraes.
Prediction: Real Betis 2-1 Vitoria Guimaraes
Telecast Details
India: Sony LIV, Sony Sports Network
UK: TNT Sports
USA: Paramount+
Nigeria: TBD
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Dilpreet is a dedicated football writer with a keen eye for World Football. As a proud Real Madrid fan, we believe his work reflects the same ambition and precision. Since joining Khel Now in 2025, he has crafted stories beyond scores, diving into tactics, culture, and emotion. With a strong background in content writing, he blends clarity with creativity, always aiming to bring the beautiful game closer to readers.
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