Preview: Arsenal vs Bayer Leverkusen Prediction, lineups, betting tips & odds | UEFA Champions League 2025-26 Round of 16 second leg

The previous outing between these sides ended in a 1-1 draw.
Arsenal are all set to have a clash against Bayer Leverkusen for their second leg round of 16 fixture of the 2025-26 UEFA Champions League. This is going to be an entertaining contest, taking place at the Emirates Stadium.
The Gunners have been in good form, but were held to a draw by the Werkself in their previous meeting. They secured an important equaliser and did not let Leverkusen take the win. The Mikel Arteta-led Arsenal will be at home for their next UCL game, and it is surely going to be a big advantage for them.
Bayer Leverkusen have been performing decently, but have not been able to bag the expected results. In their last two games, they first held the Gunners to a draw and then restricted Bayern Munich to secure a win in their Bundesliga clash. Even though the Werkself will be away from home, their confidence levels will be on the positive side for the UEFA Champions League game.
Kick-off:
- Location: London, England
- Stadium: Emirates Stadium
- Date: Wednesday, March 18
- Kick-off Time: 01:30 a.m. IST (Tuesday, Mar 17; 08:00 p.m. GMT/ 03:00 p.m. ET/ 12:00 p.m. PT)
- Referee: TBA
- VAR: In use
Form:
Arsenal: W-W-W-D-W
Leverkusen: D-W-D-D-D
Players to Watch
Viktor Gyokeres (Arsenal)

Viktor Gyokeres is going to be an important aspect of the squad in the attacking front for Arsenal. He is coming in after scoring a crucial goal in the previous Premier League match against Everton and will be eager to help his side yet again. He will be a constant threat to the opponent’s defence.
Martin Terrier (Bayer Leverkusen)

Martin Terrier will be looking to step up his game so that he can help his side stand a chance against the Gunners. He is useful both in the midfield and the final third for his side, making him a crucial part of the squad for Bayer Leverkusen. The 29-year-old will be keen to come up with a top performance and lead his side to a win away from home.
Match Facts
- Arsenal have won four of their last five matches.
- Bayer Leverkusen have finished their last three games as a draw.
- Two of the last four games between these clubs have ended on level terms.
Arsenal vs Leverkusen: Betting Tips and Odds
- Arsenal to win @3/10 William Hill
- Viktor Gyokeres to score @13/10 Unibet
- Goals under 3.5 @1/2 bet365
Injury and Team News
Mikel Merino will not be in action for Arsenal. He is injured. Martin Odegaard and Leandro Trossard might also miss out due to their lack of fitness.
Bayer Leverkusen will be without the services of Lucas Vázquez, Mark Flekken, Loic Bade, Arthur and Elieese Ben Seghir. They are injured.
Head-to-Head
Total matches: 4
Arsenal won: 2
Leverkusen won: 0
Draws: 2
Predicted Lineups
Arsenal predicted lineup (4-2-3-1)
Raya (GK); Timber, Saliba, Gabriel, Hincapié; Zubimendi, Rice; Saka, Eze, Martinelli; Gyökeres
Leverkusen predicted lineup (3-4-2-1)
Blaswich (GK); Quansah, Andrich, Tapsoba; Poku, Palacios, García, Grimaldo; Terrier, Maza; Schick
Match Prediction
Neither of these sides can afford to lose here, and it is going to be an intense game in the process. Arsenal are likely to come out on top and outplay Bayer Leverkusen in their upcoming round of 16 game of the UEFA Champions League.
Prediction: Arsenal 2-1 Leverkusen
Telecast Details
India: SonyLIV, Sony Sports Network
UK: TNT Sports, BBC
US: Paramount+, TUDN
Nigeria: DAZN
When and where is Arsenal vs Leverkusen UCL match?
Tuesday, March 17, 2026, at the Emirates Stadium in London. Kick-off is scheduled for 8:00 p.m. GMT.
Where and how to watch UEFA Champions League live in India?
SonyLIV and Sony Sports Network can be used to watch the UCL live in India.
Where and how to watch UEFA Champions League live in UK?
Fans in the United Kingdom, TNT Sports and BBC can be used to watch all the games live.
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Dilpreet is a dedicated football writer with a keen eye for World Football. As a proud Real Madrid fan, we believe his work reflects the same ambition and precision. Since joining Khel Now in 2025, he has crafted stories beyond scores, diving into tactics, culture, and emotion. With a strong background in content writing, he blends clarity with creativity, always aiming to bring the beautiful game closer to readers.