Bayer Leverkusen vs PSG Preview, prediction, lineups, betting tips & odds | UEFA Champions League 2025-26

The Parisians have scored six goals in their previous two matches against the Werkself.

Bayer Leverkusen are all set to lock horns with PSG for their Round 3 league phase fixture of the 2025-26 UEFA Champions League. This is going to be an intense fixture between these clubs, which will take place at the BayArena.

The Bundesliga side Bayer 04 Leverkusen were held to a draw in both of their first two UCL fixtures of the current season. They are going to be the hosts for their next game in the European competition. The Werkself will be keen on using it to their advantage, but it is going to be a tough challenge for them.

The defending UEFA Champions League title holders are back in action. Paris Saint-Germain have started their title defence on a positive note. The Luis Enrique-led side secured a win against Atalanta in their opening game and then took the Spanish giants Barcelona. PSG will now look to continue their winning run.

Today’s winners 🟠 https://t.co/hdZz6enyQC pic.twitter.com/EtjEGjZuq1

— Paris Saint-Germain (@PSG_English) October 18, 2025

Kick-off:

• Location: Leverkusen, Germany
• Stadium: BayArena
• Date: Wednesday, October 22
• Kick-off Time: 12:30 a.m. IST (Tuesday, Oct 21; 07:00 p.m. GMT/ 03:00 p.m. ET/ 12:00 p.m. PT)
• Referee: Jesús Gil Manzano
• VAR: In use

Form:

Leverkusen: D-W-D-W-W

PSG: L-W-W-D-D

Players to Watch

Alejandro Grimaldo (Bayer Leverkusen)

Alejandro Grimaldo has been one of the most consistent performers for Bayer Leverkusen across all competitions. He is coming in after scoring a brace in the previous fixture for his side. Grimaldo will yet again play an important role for the Bundesliga side as his work rate has been excellent.

Goncalo Ramos (PSG)

As Ousmane Dembele is still recovering from the injury, Goncalo Ramos will yet again lead Paris Saint-Germain in the attacking front. The Portuguese striker has scored two goals in two UEFA Champions League games this season. Ramos will be looking to step up and score a goal or two.

Match Facts

• Bayer Leverkusen haven’t lost any of their last eight matches.
• Paris Saint-Germain have won the previous two matches against Die Werkself.
• PSG have failed to secure a win in their last two fixtures.

Leverkusen vs PSG: Betting Tips and Odds

• PSG to win @13/20 Ladbrokes
• Goncalo Ramos to score @19/4 Unibet
• Goals under 3.5 @3/5 Betway

Injury and Team News

Bayer Leverkusen will not have Lucas Vazquez, Malik Tilman, Patrik Schick, Nathan Tella, Exequiel Palacios, Axel Tape-Kobrissa and Jarell Quansah as they are injured.

Speedy recovery, Malik 💪Our no.10 is expected to be out for around two weeks with a thigh muscle injury. pic.twitter.com/Gm3BiUPAnm

— Bayer 04 Leverkusen (@bayer04_en) October 19, 2025

Ousmane Dembele, Marquinhos, Fabian Ruiz and Joao Neves will not be in action for PSG as they are injured.

Head-to-Head

Total matches: 2

Leverkusen won: 0

PSG won: 2

Draws: 0

Predicted Lineups

Bayer Leverkusen predicted lineup (3-4-2-1)

Flekken (GK); Andrich, Badé, Tapsoba; Arthur, Fernandez, Garcia, Grimaldo; Hofmann, Poku; Kofane

PSG predicted lineup (4-3-3)

Chevalier (GK); Hakimi, Pacho, Beraldo, Mendes; Zaire-Emery, Mayulu, Vitinha; Doue, Ramos, Barcola

Match Prediction

This will be only the third encounter between these clubs, but Paris Saint-Germain are likely to come out on top yet again to secure a win against Bayer 04 Leverkusen in their upcoming UEFA Champions League clash.

Prediction: Leverkusen 1-2 PSG

Telecast Details

India: SonyLIV, Sony Sports Network

UK: TNT Sports, Amazon Prime, BBC

US: Paramount+, TUDN

Nigeria: DAZN

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