Benfica vs Bayer Leverkusen Preview, prediction, lineups, betting tips & odds | UEFA Champions League 2025-26

The previous confrontation between these clubs ended in a goalless draw.

SL Benfica will now gear up to face Bayer Leverkusen in their round 4 league phase fixture of the 2025-26 UEFA Champions League. This is going to be an interesting and intense outing between these clubs, which will take place at Estádio da Luz.

The Jose Mourinho-led Benfica have lost all of their first three games of the European competition this season. They have lost to FK Qarabag, Chelsea and Newcastle United. The Liga Portugal club will be at home for their next outing and will be looking to give their all for a win.

The Bundesliga side have also not been able to secure any positive results in their ongoing UEFA Champions League campaign. Bayer Leverkusen were held to a draw in their first two games and faced a dominating defeat in their third UCL game of this season against Paris Saint-Germain.

Kick-off:

• Location: Lisbon, Portugal
• Stadium: Estadio da Luz
• Date: Thursday, November 6
• Kick-off Time: 1:30 a.m. IST (Wednesday, Nov 5; 08:00 p.m. GMT/ 04:00 p.m. ET/ 01:00 p.m. PT)
• Referee: Simone Sozza
• VAR: In use

We're off to Lisbon next! 🇵🇹#UCL #aCROSSeurope #SLBB04 pic.twitter.com/Cz6Qu5AFnW

— Bayer 04 Leverkusen (@bayer04_en) November 3, 2025

Form:

Benfica: W-L-W-W-W

Leverkusen: W-L-W-W-L

Players to Watch

Vangelis Pavlidis (Benfica)

Vangelis Pavlidis must step up for his side. He is one of their main men in the attacking front. Although the 26-year-old has come up with decent performances domestically, he has not been the best in the Champions League.

He will be keen on finding the net this time around.

Aleix García (Bayer Leverkusen)

The 28-year-old midfielder is coming in after scoring a brace against PSG, which was obviously not enough as Leverkusen lost that game by 2-7. Aleix Garcia will be looking to come up with another similar performance, which can hopefully help his side secure three points.

Match Facts

• SL Benfica have not conceded any goals in four of their last five matches.
• Bayer Leverkusen have conceded 15 goals in their last five games.
• These clubs are going to face each other for the fifth time across all competitions.

Benfica vs Bayer Leverkusen: Betting Tips and Odds

• Benfica to win @11/10 Ladbrokes
• Vangelis Pavlidis to score @9/2 bet365
• Goals under 3.5 @10/21 Unibet

Injury and Team News

Manu Silva and Amar Dedic will not be in action for Benfica as they are injured. Alexander Bah and Bruma might also miss out due to their fitness issues.

Bayer Leverkusen will be without the services of Lucas Vazquez, Equi Fernandez, Exequiel Palacios, Nathan Tella and Axel Tape-Kobrissa. They are injured.

Malik Tillman might also sit out due to a lack of fitness. Robert Andrich is suspended.

Head-to-Head

Total matches: 4

Benfica won: 2

Leverkusen won: 1

Draws: 1

Predicted Lineups

Benfica predicted lineup (4-2-3-1)

Trubin (GK); Aursnes, Araujo, Otamendi, Dahl; Rios, Barrenechea; Lukebakio, Sudakov, Prestianni; Pavlidis

Leverkusen predicted lineup (3-4-2-1)

Flekken (GK); Quansah, Bade, Tapsoba; Arthur, Garcia, Maza, Grimaldo; Hofmann, Poku; Schick

Match Prediction

Both of these clubs are looking for a win. We predict SL Benfica to come out on top to secure a victory against Bayer Leverkusen in their upcoming UEFA Champions League clash.

Prediction: Benfica 2-1 Leverkusen

Telecast Details

India: SonyLIV, Sony Sports Network

UK: TNT Sports, Amazon Prime, BBC

US: Paramount+, TUDN

Nigeria: DAZN

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