Liverpool vs Atlético Madrid Preview, prediction, lineups, betting tips & odds | UEFA Champions League 2025-26

The Reds secured an easy win when these sides last met.

Liverpool are ready to battle it out against Atletico Madrid in their matchweek 1 league phase fixture of the 2025-26 UEFA Champions League. Anfield is all set to witness the interesting clash.

The Arne Slot-led side will be at home and this is going to be a big advantage for them. Liverpool will be feeling confident due to their last couple of results against Atleti. The Reds have been doing well in the Premier League and will be looking to continue their form coming into the European competition.

Atletico Madrid are coming in after securing a 2-0 win against Villarreal in their previous LaLiga game. The Diego Simeone-led side have not started their new season as they might have wanted. The Spanish side will be looking to step up and come up with a unique strategy if they want to stand a chance against the Reds.

Kick-off:

• Location: Liverpool, England
• Stadium: Anfield
• Date: Thursday, September 18
• Kick-off Time: 12:30 a.m. IST (Wednesday, Sept 17; 07:00 p.m. GMT/ 03:00 p.m. ET/ 12:00 p.m. PT)
• Referee: Maurizio Mariani
• VAR: In use

Form:

Liverpool: W-W-W-W

Atletico Madrid: L-D-D-W

Players to Watch

Mohamed Salah (Liverpool)

The Egyptian winger is going to play an important role in the attacking front for the Reds. Mohamed Salah is coming in after converting a match-winning spot kick in his previous game. He will be looking to yet again engrave his name on the scoresheet so that he can help his side.

Start your week right with another look at Mo's winning goal 🤩 pic.twitter.com/dvBOcIyyMv

— Liverpool FC (@LFC) September 15, 2025

Pablo Barrios (Atletico Madrid)

In three LaLiga appearances, the 22-year-old Spanish midfielder has performed well for Atletico Madrid. Pablo Barrios scored one of the goals in Atleti’s 2-0 win against Villarreal. He will have a major role in regulating the ball in the midfield. Barrios can also be of use in the final third.

Match Facts

• The Reds have won three of their last five matches against Atleti.
• Atletico Madrid have only won one of their last five fixtures against Liverpool.
• The Arne Slot-led side are on a four-match winning streak.

Liverpool vs Atletico Madrid: Betting Tips and Odds

• Liverpool to win @3/5 BetFred
• Mo Salah to score @9/2 bet365
• Goals over 3.5 @13/8 bet365

Injury and Team News

Curtis Jones and Stefan Bajcetic might miss out on action due to fitness issues. Alexander Isak will not be in action due to personal reasons.

Atletico Madrid will be without the services of Alex Baena as he is injured. David Hancko, Jose Gimenez and Thiago Almada might also miss out due to a lack of fitness.

Head-to-Head

Total matches: 10

Liverpool won: 3

Atletico won: 4

Draws: 3

Predicted Lineups

Liverpool predicted lineup (4-2-3-1)

Alisson (GK); Szoboszlai, Konaté, Van Dijk, Kerkez; Gravenberch, Mac Allister; Salah, Wirtz, Gakpo; Ekitike

Atletico Madrid predicted lineup (4-4-2)

Oblak (GK); Llorente, Le Normand, Lenglet, Ruggeri; Simeone, Barrios, Koke, González; Griezmann, Alvarez

Match Prediction

These clubs are all set to produce an intense fixture, but Liverpool will be coming in as the favourites and are likely to secure a win in their opening UEFA Champions League clash against Atletico Madrid.

Prediction: Liverpool 3-1 Atletico Madrid

Telecast Details

India: SonyLIV, Sony Sports Network

UK: TNT Sports, BBC

US: Paramount+, TUDN

Nigeria: DAZN

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