Liverpool vs Real Madrid Preview, prediction, lineups, betting tips & odds | UEFA Champions League 2025-26

Liverpool have struggled of late, but Real Madrid have been cruising in all competitions
Anfield will be the home of European football yet again for a high-profile clash which will see Liverpool host Real Madrid in the UEFA Champions League. This will be a battle between two sides having different fortunes so far. One side is struggling, while the other side is just flowing.
Liverpool have shown their dominance at certain moments but have not found the consistency. However, their recent 2-0 win against Aston Villa in the Premier League will definitely calm their nerves and provide them with confidence ahead of this high-intensity clash.
Meanwhile, Los Blancos will approach the fixture with the confidence of a team that knows how to win. They have swept through their recent matches with dominance, holding a perfect European record and five straight victories in all competitions.
Kylian Mbappé will lead their attack with decisiveness and relentlessness in front of goal, while the defence has kept its composure and allowed just one goal in three Champions League games.
History turns this clash into more than just another contest. Liverpool still feel the scars from the 2018 and 2022 final defeats, moments that cut deep into their memory. Even so, Anfield’s energy can rewrite any script. Mohamed Salah will yet again carry Liverpool’s hopes with his sharp instincts and composure that spark belief.
Slot will demand intensity, aggression, and faith from his players. The challenge looms large, but so does the chance to reclaim pride and remind Europe that Anfield still makes even giants tremble.
Kick-off:
- Location: Liverpool, England
- Stadium: Anfield
- Date: Wednesday, November 5
- Kick-off Time: 1:30 a.m. IST
- Referee: François Letexier
- VAR: In use
Form:
Liverpool (in all competitions): W-L-L-W-L
Real Madrid (in all competitions): W-W-W-W-W
Players to Watch:
Mohamed Salah ( Liverpool):

Mohamed Salah will be the player to watch because he thrives under pressure and delivers in big moments. His sharp movement, quick decisions, and lethal finishing can trouble even the best defences.
With Anfield behind him, Salah’s hunger to avenge past defeats against Madrid could define Liverpool’s performance on the night. The Egyptian winger has scored five goals and provided three assists in 14 matches so far in all competitions.
Kylian Mbappe (Real Madrid):

Kylian Mbappe will be the key threat for Madrid because his pace, timing, and precision make him almost impossible to contain. He breaks lines effortlessly and punishes the smallest defensive lapse.
In his current form, every run and touch from Mbappe carries danger, giving Madrid their sharpest edge at Anfield. The Frenchman has scored 18 goals and provided 12 assists in 14 across competitions so far this season.
Match Facts:
- Real Madrid holds a perfect record in the 2025/26 Champions League season with nine points from three matches, while Liverpool’s recent form, including a poor domestic run, has been inconsistent.
- The Champions League clash will mark a significant return for the ex-Liverpool vice-captain after his transfer to Los Blancos.
- Despite their domestic struggles, Liverpool have scored eight goals in their three Champions League matches but have also conceded four.
Liverpool vs Real Madrid Betting Tips and Odds:
- Liverpool to win: 1.85 as per 1xBet.
- Both teams to score: 1.72 as per Winmatch.
- Total goals over 2.5: 1.97 as per 1Win.
Team News:

Liverpool face several injury concerns ahead of the Madrid clash. Alisson Becker and Stefan Bajcetic remain out until late November, while Jeremie Frimpong targets a mid-December return. Giovanni Leoni continues recovery from a cruciate ligament injury. Curtis Jones is a doubt with a knock, and Alexander Isak misses out due to a groin issue.
Real Madrid have a few fitness worries before their trip to Anfield. Daniel Carvajal remains sidelined with a knee injury until early January. Antonio Rüdiger is recovering from a leg problem and could return by mid-November. David Alaba faces a late fitness test after a muscle issue left his availability uncertain. Franco Mastantuono has been ruled out due to an injury.
Head-To-Head stats:
- Total matches: 11
- Liverpool won: 3
- Real Madrid won: 7
- Draws: 1
Predicted Starting Lineups:
Liverpool Predicted Starting Lineups (4-2-3-1):
G. Mamardashvili; C. Bradley, I. Konaté, V. van Dijk, A. Robertson; R. Gravenberch, A. Mac Allister; M. Salah, D. Szoboszlai, C. Gakpo; H. Ekitike
Real Madrid Predicted Starting Lineups (4-3-3):
T. Courtois; F. Valverde, É. Militão, D. Huijsen, A. Carreras; A. Güler, A. Tchouaméni, J. Bellingham; Brahim, K. Mbappé, V. Júnior
Match Prediction:
It is going to be a very even contest despite Liverpool’s recent struggles in the league. However, we feel like the Anfield atmosphere will give the home side a slight edge in this game.
Prediction: Liverpool 2-1 Real Madrid
Telecast Details
India: SonyLIV, Sony Sports Network
UK: TNT Sports, Amazon Prime, BBC
US: Paramount+, TUDN
Nigeria: DAZN
What time is kick-off?
The kick-off is at 1:30 AM IST on November 5, 2025
Who are the key players returning to Anfield?
Real Madrid manager Xabi Alonso and former Liverpool vice-captain Trent Alexander-Arnold will both be returning to Anfield.
What is Real Madrid’s recent Champions League form?
Real Madrid have a perfect Champions League record, earning nine points in their first three matches.
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