Preview: Manchester City vs Real Madrid Prediction, lineups, betting tips & odds | UEFA Champions League 2025-26 Round of 16 second leg

The Cityzens have only defeated Los Blancos once in the last five occasions.
Manchester City are all set to lock horns with Real Madrid for their second leg round of 16 fixture of the 2025-26 UEFA Champions League. This high-voltage clash will be witnessed at the Etihad Stadium.
The Cityzens have failed to secure a win in their last two matches. They will be in a tough position coming for their second leg against Madrid in the UCL.
They are going to be the hosts, but are already down by three goals. The Pep Guardiola-led side must come up with a top performance if they want to turn the tide around.
Real Madrid have secured back-to-back wins in their last three games. They will be full of confidence for their next one despite being away from home.
They surely have the advantage in their hands, but Los Blancos must not give many chances to Manchester City. Anyhow, the 15-time UEFA Champions League winners will be coming in with full force here.
Kick-off:
- Location: Manchester, England
- Stadium: Etihad Stadium
- Date: Wednesday, March 18
- Kick-off Time: 01:30 a.m. IST (Tuesday, Mar 17; 08:00 p.m. GMT/ 03:00 p.m. ET/ 12:00 p.m. PT)
- Referee: TBA
- VAR: In use
Form:
Man City: W-D-W-L-D
Madrid: W-L-W-W-W
Players to Watch
Erling Haaland (Man City)

The 25-year-old Norwegian forward will be looking to step up his game and help his side make a comeback. Even though he hasn’t been very consistent with his performances in the last three games for Manchester City, Erling Haaland is a capable player. He will be eager to help his side by scoring a goal or two.
Federico Valverde (Real Madrid)

Federico Valverde has now scored in back-to-back games for Real Madrid. He has netted five goals in the last three games for his club and is going to be a constant threat to the opponent’s defence. Valverde is doing well in the midfield and is surely capable of scoring goals.
He is going to play a crucial role for Los Blancos once again.
Match Facts
- Real Madrid are on a three-match winning streak.
- Manchester City are winless in their last two games.
- Los Blancos have won four of their last five fixtures against the Cityzens.
Man City vs Real Madrid: Betting Tips and Odds
- Real Madrid to win @9/2 Ladbrokes
- Vini Jr. to score @3/1 Virgin Bet
- Goals over 3.5 @13/10 BetMGM
Injury and Team News
Manchester City will be without the services of Josko Gvardiol and Rico Lewis. They are injured.
Jude Bellingham, Rodrygo, Dani Ceballos, David Alaba, Alvaro Carreras and Ferland Mendy are not going to be in action for Real Madrid due to their injuries. Eder Militao and Raul Asencio are not yet confirmed to be a part of the squad. Kylian Mbappe could feature here.
Also read: What role could Kylian Mbappe play against Man City in Champions League: Revealed
Head-to-Head
Total matches: 16
Man City won: 5
Madrid won: 7
Draws: 4
Predicted Lineups
Man City predicted lineup (4-1-3-2)
Donnarumma (GK); Nunes, Dias, Guehi, O’Reilly; Rodri; Semenyo, Silva, Doku; Marmoush, Haaland
Real Madrid predicted lineup (4-4-2)
Courtois (GK); Trent, Rudiger, Huijsen, Garcia; Valverde, Guler, Tchouaméni, Camavinga; Diaz, Vini Jr.
Match Prediction
These sides are going to come up with a high-voltage clash. Real Madrid are likely to come out on top to outplay Manchester City in their upcoming UEFA Champions League clash.
Prediction: Man City 2-3 Madrid
Telecast Details
India: SonyLIV, Sony Sports Network
UK: TNT Sports, BBC
US: Paramount+, TUDN
Nigeria: DAZN
When and where is Man City vs Real Madrid UCL match?
Tuesday, March 17, 2026, at the Etihad Stadium in Manchester. Kick-off is scheduled for 8:00 p.m. GMT.
Where and how to watch UEFA Champions League in India?
SonyLIV and Sony Sports Network can be used to watch the UCL live in India.
Where and how to watch UEFA Champions League in UK?
Fans in the United Kingdom, TNT Sports and BBC can be used to watch all the games live.
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Dilpreet is a dedicated football writer with a keen eye for World Football. As a proud Real Madrid fan, we believe his work reflects the same ambition and precision. Since joining Khel Now in 2025, he has crafted stories beyond scores, diving into tactics, culture, and emotion. With a strong background in content writing, he blends clarity with creativity, always aiming to bring the beautiful game closer to readers.