Preview: Manchester City vs Southampton Prediction, lineups, betting tips & odds | FA Cup 2025-26 semi-final

The Cityzens are unbeaten in their last three clashes against the Saints.
Manchester City are now going to battle it out against Southampton FC for the semifinal contest of the 2025-26 FA Cup. These clubs are going to produce an intense clash, taking place at Wembley Stadium.
The Pep Guardiola-led side have performed well in their last five matches. They are coming in after securing back-to-back wins and will be looking for another one in their next fixture. The Cityzens are now even leading the Premier League standings.
Manchester City knocked out Liverpool in their previous round of the oldest club cup competition. They will now be keen to secure a spot in the final of the tournament.
The Saints are on a phenomenal run of form and will surely be confident for their next one. In the FA Cup quarterfinal, they outplayed Arsenal after displaying a top performance. Tonda Eckert’s men will be looking to put up a strong fight against Man City as well.
It will be a tough outing for them. Southampton FC must use their ongoing momentum. With their current form, they might have a chance against the Cityzens.
Kick-off:
- Location: London, England
- Stadium: Wembley Stadium
- Date: Saturday, April 25
- Kick-off Time: 09:45 PM IST/ 04:15 PM GMT/ 11:15 AM ET/ 08:15 AM PT
- Referee: Craig Pawson
- VAR: In use
Form:
Man City: W-W-W-W-W
Southampton: W-W-W-W-D
Players to Watch
Erling Haaland (Manchester City)

Erling Haaland is going to play an important role in the attacking front for Manchester City. He is coming in after scoring in back-to-back games for the Cityzens. The former Dortmund forward will be looking to add more to his tally.
The Norwegian player has scored three goals in two FA Cup games this season and is going to be a constant threat to the opponent’s defence.
Cyle Larin (Southampton)
Cyle Larin is on a decent run of form at the moment and is going to be a crucial asset in the final third for Southampton FC. Although he has only scored one goal in the ongoing campaign of the oldest cup competition, the 31-year-old will be eager to trouble Man City.
Match Facts
- Manchester City are on a five-match winning streak.
- Southampton FC are unbeaten in their last 20 matches.
- The Saints have only secured one win in their last five attempts against the Cityzens.
Man City vs Southampton: Betting Tips and Odds
- Manchester City to win @3/13 Unibet
- Erling Haaland to score @40/85 BetVictor
- Goals over 3.5 @21/20 William Hill
Injury and Team News
Josko Gvardiol, Rodri and Ruben Dias are not going to be in action for Manchester City. They are injured and are likely to return to action during early to mid-May 2026.
Southampton FC will be without the services of Alex McCarthy and Mads Roerslev due to their injuries.
Head-to-Head
Total matches: 103
Man City won: 42
Southampton won: 33
Draws: 28
Predicted Lineups
Man City predicted lineup (4-2-3-1)
Donnarumma (GK); Nunes, Khusanov, Guéhi, O’Reilly; Silva, Reijnders; Semenyo, Cherki, Doku; Haaland
Southampton predicted lineup (4-4-2)
Peretz (GK); Bree, Harwood-Bellis, Wood, Manning; Matsuki, Downes, Charles, Azaz; Archer, Larin
Match Prediction
Both of these clubs are in a top run of form. At Wembley Stadium, Manchester City and Southampton FC are going to produce an intense contest.
The Cityzens are likely to outplay the Saints and secure a spot in the FA Cup final.
Prediction: Man City 3-1 Southampton
Telecast Details
India: Sony LIV, Sony Sports Network
UK: TNT Sports, BBC
USA: ESPN+
Nigeria: StarTimes
When and where is Man City vs Southampton FA Cup semifinal?
Saturday, April 25, at Wembley Stadium in London, England. Kick-off is scheduled for 4:15 p.m. GMT.
Where and how to watch FA Cup live in India?
Fans can tune into Sony LIV and Sony Sports Network to watch the competition live.
Where and how to watch FA Cup live in UK?
TNT Sports and BBC can be used to watch all the games live.
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Dilpreet is a dedicated football writer with a keen eye for World Football. As a proud Real Madrid fan, we believe his work reflects the same ambition and precision. Since joining Khel Now in 2025, he has crafted stories beyond scores, diving into tactics, culture, and emotion. With a strong background in content writing, he blends clarity with creativity, always aiming to bring the beautiful game closer to readers.