Manchester United vs Chelsea Preview, prediction, lineups, betting tips & odds | Premier League 2025-26

The Blues came out victorious when they last faced the Red Devils.

Manchester United are all set to battle it out against Chelsea in the matchweek 5 fixture of the 2025 -26 English Premier League. Old Trafford is all set to witness the intense clash between these clubs.

The Ruben Amorim-led side will be under pressure despite being at home. The Red Devils fell prey to Manchester City in their previous league game. It was an underwhelming performance by Manchester United. For their upcoming game, they must come up with a different strategy if they want to stand a chance.

In the gym 💪 pic.twitter.com/gZcG61Y60v

— Manchester United (@ManUtd) September 17, 2025

Chelsea are coming in after facing a defeat in their UEFA Champions League fixture against Bayern Munich. The Blues did not perform up to the mark, which led to their defeat. The Enzo Maresca-led side are still unbeaten in the Premier League this season. Even though they will be away from home, Chelsea will be confident.

Kick-off:

• Location: Manchester, England
• Stadium: Old Trafford
• Date: Saturday, September 20
• Kick-off Time: 10:00 p.m. IST/ 04:30 p.m. GMT/ 12:30 p.m. ET/ 09:30 a.m. PT
• Referee: Peter Bankes
• VAR: In use

Form:

Man United: L-D-L-W-L

Chelsea: D-W-W-D-L

Players to Watch

Bryan Mbeumo (Man Utd)

Bryan Mbeumo is going to play an important role in the attacking front for Manchester United. Even though he has only scored a single goal in their four Premier League appearances, his presence in the attacking front has always been an issue for the opponent’s defence.

Joao Pedro (Chelsea)

The 23-year-old Brazilian forward has been one of the most consistent players for Chelsea. Joao Pedro is yet again ready to help his side on the attacking front. In four league games, he has scored two goals and has three assists to his name. Pedro is going to be a constant threat to Man United.

Match Facts

• Manchester United have failed to secure a clean sheet in any of their last five matches.
• Both Chelsea and the Red Devils have won two matches each in their last five meetings against one another.
• The Blues have scored 10 goals in their last five matches.

Man Utd vs Chelsea: Betting Tips and Odds

• Manchester United to win @9/5 BetFred
• Bryan Mbeumo to score @17/2 Unibet
• Goals over 3.5 @31/20 BetMGM

Injury and Team News

Lisandro Martinez and Diogo Dalot will not be in action for Man United as they are injured. Matheus Cunha and Mason Mount are back training with the first team and but are most likely not to start in the upcoming fixture.

Chelsea will be without the services of Liam Delap, Levi Colwill, Dario Essugo, Benoit Badiashile and Romeo Lavia as they are injured.

Head-to-Head

Total matches: 194

Man Utd won: 83

Chelsea won: 55

Draws: 56

Predicted Lineups

Man United predicted lineup (3-4-2-1)

Lammens (GK); Yoro, De Ligt, Shaw; Amad, Casemiro, Mainoo, Dorgu; Mbeumo, Fernandes; Sesko

Chelsea predicted lineup (4-2-3-1)

Sánchez (GK); Gusto, Chalobah, Adarabioyo, Cucurella; James, Caicedo; Palmer, Fernández, Neto; João Pedro

Match Prediction

These England-based clubs are going to produce an interesting fixture here. Manchester United are likely to come out on top to secure a win against Chelsea in their upcoming Premier League clash.

Prediction: Man United 3-2 Chelsea

Telecast Details

India: JioHotstar, Star Sports Network

UK: TNT Sports and Sky Sports

USA: NBC Sports

Nigeria: SuperSport

For more updates, follow Khel Now on Facebook, Twitter, and Instagram; download the Khel Now Android App or IOS App and join our community on Telegram.