Santos vs Sao Paulo Preview, prediction, lineups, betting tips & odds | Brazilian Serie A 2025

Coach Juan Pablo Vojvoda will rely on Neymar’s experience to thwart an impending São Paulo attack at home.

Neymar’s FC Santos will host Sao Paulo in their upcoming match in the Brazilian Serie A. The Peixe, who are dangerously hovering over the relegation zone, would need a much-needed win if they hope to steer clear of the dreaded red line.

The “Alvinegro” are in 16th position, just a point more than Vitoria with 23 points. The club have been seemingly struggling this year and have salvaged just six wins out of its 22 games. Their last four games have not seen them finish in the winners’ bracket, and they had to settle for back-to-back losses and draws.

Sao Paulo, on the other hand, are doing a far better job on the table. Similar to their last year’s performance, they are in the top 10. Placed in the seventh spot, they have accumulated 35 points so far and would look to break into the top five.

Kick-off:

• Location: Santos, Brazil
• Stadium: Estadio Urbano Caldeira
• Date: Monday, September 22
• Kick-off Time: 05:00 a.m. IST
• Referee: Rodrigo José Pereira de Lima
• VAR: In use

Form:

FC Santos: L-L-L-D-D

Sao Paulo FC: D-W-W-L-W

Players to Watch

Neymar Jr (FC Santos)

Once Santos’s prodigal talent and now captain, Neymar Jr, can prove to be the game-changer in this crucial match against Sao Paulo. The former youth product returned to his boyhood club and marked a historic moment in doing so as the gallery erupted to welcome him in a match against Botafogo SP.

Neymar, now a senior player, can definitely shake things up with his performance for the club. This is more so applicable in his backyard, which introduced him to football. The attacking midfielder has so far made 246 appearances for the club and scored 142 goals.

Juan Dinneno (Sao Paolo)

Sao Paulo striker Juan Dinneno will be expected to score here after his match-winning performance against Botafogo. The Argentinian is an experienced campaigner and has played for teams like Racing Club, Deportivo Cali, UNAM, and Cruzeiro; among others.

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— São Paulo FC (@SaoPauloFC) September 14, 2025

Match Facts

• When playing at home, Santos have not lost to Sao Paulo in their last 3 encounters.
• Sao Paulo SP haven’t scored in 4 of their 11 away matches in the Brasileiro Serie A this season.
• The average number of goals in meetings between Santos and Sao Paulo is 2.6.

FC Santos vs Sao Paulo Betting Tips and Odds

• Match to end in a 0-0 draw @7.60 Stake
• Total corners to be taken 17+ over @2.02
• Both teams to keep a clean sheet

Injury and Team News

In the Santos squad, Willian Arao will miss out because of a calf injury.

In Sao Paulo’s team, Luiz Gustavo, Jonathan Calleri, Ryan Francisco, Oscar, Lucas Moura, Andre Silva and Ferreirinha are out with injuries.

Head-to-Head

Total Matches: 65

FC Santos won: 29

Sao Paulo won: 25

Draws: 14

Predicted Lineups

FC Santos predicted lineup (4-4-2)

Brazao (GK); Escobar, Peres Petroni, Ivaldo, Vinicius; Guilherme, Ze Rafael, Schimdt, Hugo; Neymar, Diaz

Sao Paulo FC (3-4-1-2)

Rafael (GK); Toloi, Franco, Sabino; Cedric, Allison, Maia, Diaz;Rodriguinho; Tapia, Dinenno

Match Prediction

Despite the visitors looking much better on paper against the hosts, it seems that the match will end in a goalless draw. FC Santos will surely look to up the ante as they have found themselves in a predicament and would not settle for anything less than a win. However, that won’t come easily against a team (Sao Paulo) that is in great form at the moment.

Prediction: FC Santos 0 – 0 Sao Paulo FC

Telecast Details

USA: Fanatiz

UK: Onefootball app & website

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