Seattle Sounders vs Cruz Azul Prediction, lineups, betting tips & odds

This will be the first time these teams face off against one another.
Seattle Sounders FC are all set to host Cruz Azul in the first leg of the CONCACAF Champions Cup 2025 round of 16. The hosts dominated Antigua GFC in the first round and made progress in the tournament. The visitors on the other hand easily took down Real Hope in the first round.
Seattle Sounders will be at their home but will be slightly low on confidence as they are coming in after facing a defeat against Real Salt Lake. Although they secured an easy win in their last Champions Cup match, Cruz Azul are not going to be an easy contest for them.
The Liga MX side Cruz Azul will be confident enough as they are undefeated in their last three league games. The visitors are going to give a tough fight to Seattle Sounders FC as they are not very consistent as of now. They will have to take advantage of the situation and will look to come up with some top plays.
Kick-off:
- Location: Seattle, Washington
- Stadium: Lumen Field
- Date: Thursday, March 6
- Kick-off Time: 09:00 IST/ 03:30 GMT / Wednesday, March 5: 22:30 ET/ 19:30 PT
- Referee: TBD
- VAR: In use
Form:
Seattle Sounders: D-W-D-W-L
Cruz Azul: W-L-W-W-D
Players to Watch
Pedro de la Vega (Seattle Sounders FC)
In the first round of the CONCACAF Champions Cup 2025, the Argentina forward scored three goals. Pedro de la Vega is going to play an important role once again. He is good at the attacking front.
Although he is yet to open his account in the MLS 2025 season, Pedro can step up and score goals for his side to put them in an advantage.
Angel Sepulveda (Cruz Azul)
Angel Sepulveda is the top goal scorer in the Champions Cup for Cruz Azul. He has scored a couple of goals in two games. The Mexican forward is experienced and knows how to get through the defenders.
Match Facts
- Seattle Sounders have been unable to maintain a clean sheet in their nine matches in all competitions.
- They have two wins in their last five matches.
- Cruz Azul smashed five goals against Real Hope in the first round second leg.
Seattle Sounders vs Cruz Azul: Betting Tips and Odds
- Match to end in a draw
- Goals over 3.5
- Angel Sepulveda to score
Injury and Team News
Reed Baker-Whiting is injured and will not be a part of the Seattle Sounders FC lineup.
Cruz Azul will be without the services of Mateo Levy because of an injury.
Head-to-Head
This is the first time that Seattle Sounders vs Cruz Azul are going to take on one another.
Predicted Lineups
Seattle Sounders predicted lineup (4-2-3-1)
Frel (GK); Kossa-Rienzi, Gomez, Bell, Tolo; Roldan, Vargas; Pedro de la Vega, Rusnak, Rothrock; Morris
Cruz Azul predicted lineup (3-4-3)
Gudino (GK); Garcia, Lira, Piovi; Rivero, Montano, Faravelli, Campos; Sepulveda, Fernandez, Bogusz
Match Prediction
Both sides are coming in after securing dominating wins in the first round of the CONCACAF Champions Cup 2025. For the round of 16 first leg, Seattle Sounders vs Cruz Azul might end in a draw.
Prediction: Seattle Sounders 2-2 Cruz Azul
Telecast Details
India: Fancode
USA: FS2, TUDN
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