Latest betting odds for UFC 322 Della Maddalena vs Islam Makhachev

UFC has arrived in the Big Apple for a blockbuster card this weekend.

Something special always happens when the UFC returns to New York City each November, and UFC 322: Della Maddalena vs Makhachev promises to keep that tradition alive this year.

Taking place at the iconic Madison Square Garden, the VeChain-sponsored event features a blockbuster lineup headlined by two superfights that could redefine the sport’s elite landscape.

In the main event, Welterweight Champion Jack Della Maddalena takes on former lightweight king Islam Makhachev, who is on a bid to become a two-division champion.

FOR WELTERWEIGHT GOLD 🏆Jack Della Maddalena vs @MAKHACHEVMMA[ #VeChain #UFC322 | NOV 15 | 10pmET on @ESPN PPV ] pic.twitter.com/FoF9rKqxLc

— UFC (@ufc) November 13, 2025

Meanwhile, in the co-main event, Zhang Weili moves up to face Flyweight Queen Valentina Shevchenko in a historic champion-versus-champion showdown.

From rising stars like Sean Brady and Michael Morales to fan favorites like Bo Nickal and Erin Blanchfield, the card is stacked from top to bottom. With gold, glory, and legacy on the line, UFC 322 is shaping up as one of the year’s must-watch fight nights, a true showcase of the sport’s best on its biggest stage.

All the fights have a sense of unpredictability to them. However, BetOnline.ag has provided the current betting odds for the stacked card, which give an idea about oddsmakers’ picks for the winners, so let’s have a look at them.

Two belts are on the line 🏆🏆Here's the #VeChain #UFC322 championship fighters most notable wins![ B2YB: @ARCRaidersGame ] pic.twitter.com/LS9gfMyUp0

— UFC (@ufc) November 14, 2025

Also Read: UFC 322 Della Maddalena vs Makhachev: Preview, fight card, start time, where to watch & more

Current betting odds for UFC 322: Della Maddalena vs Makhachev

Main Card

Jack Della Maddalena (c) vs Islam Makhachev – Welterweight title fight

Jack Della Maddalena (c): +245

Islam Makhachev: -285

Valentina Shevchenko (c) vs Zhang Weili – Women’s Strawweight title fight

Valentina Shevchenko (c): -134

Zhang Weili: +114

Sean Brady vs Michael Morales – Welterweight bout

Sean Brady: -130

Michael Morales: +110

Leon Edwards vs Carlos Prates – Welterweight bout

Leon Edwards: +143

Carlos Prates: -163

Beneil Dariush vs Benoit Saint-Denis – Lightweight bout

Beneil Dariush: +155

Benoit Saint-Denis: -180

Preliminary card

Bo Nickal vs Rodolfo Vieira – Middleweight bout

Bo Nickal: -225

Rodolfo Vieira: +190

Roman Kopylov vs Gregory Rodrigues – Middleweight bout

Roman Kopylov: +160

Gregory Rodrigues: -185

Erin Blachfield vs Tracy Cortez – Women’s flyweight bout

Erin Blachfield: -250

Tracy Cortez: +210

Malcolm Wellmaker vs Ethyn Ewing – Men’s bantamweight bout

Malcolm Wellmaker: -550

Ethyn Ewing: +400

Also Read: UFC 322: Entrance songs for all fighters, Jack Della Maddalena, Islam Makhachev & more

Early Prelims card

Kyle Daukaus vs Gerald Meerschaert – Middleweight bout

Kyle Daukaus: -500

Gerald Meerschaert: +375

Pat Sabatini vs Chepe Mariscal – Featherweight bout

Pat Sabatini: -130

Chepe Mariscal: +110

Angela Hill vs Fatima Kline – Women’s Strawweight bout

Angela Hill: +400

Fatima Kline: -550

Baisangur Susurkaev vs Eric McConico – Middleweight bout

Baisangur Susurkaev: -1000

Eric McConico: +700

Viacheslav Borshchev vs Matheus Camilo – Lightweight bout

Viacheslav Borshchev: +145

Matheus Camilo: -170

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