Preview: Real Betis vs Atletico Madrid Prediction, lineups, betting tips & odds | Copa del Rey 2025-26

Both sides are to meet each other twice in 72 hours.
The Estadio La Cartuja de Sevilla in Seville, Spain, gears up to host the Copa del Rey quarter-final fixture between home team Real Betis and Atlético Madrid.
Real Betis are coming after edging past Real Murcia and Elche in the previous knockout rounds to make it to the quarter-finals. They are positioned fifth in the LaLiga points table. They are led by Chilean gaffer Manuel Pellegrini, who has previously led teams like Manchester City, Real Madrid, and West Ham United FC.
Atletico Madrid got the better of Ourense and Deportivo in the previous rounds. They are coming after a shocking defeat to Bodo/Glimt in the UEFA Champions League. Diego Simeone’s men will be keen to get back to winning ways with a win over Real Betis and secure their place in the semi-finals.
Kick-off:
- Location: Sevilla, Spain
- Stadium: Estadio La Cartuja de Sevilla
- Date: Friday, February 6
- Kick-off Time: 1:30 a.m. IST
- Referee: TBD
- VAR: In use
Players to Watch
Antony (Real Betis)

The Brazilian winger has plied his trade with teams like AFC Ajax and Manchester United before making a permanent move to Real Betis in 2025. He will be tasked with the responsibility of making those overlapping runs from the wings and creating chances. In 17 games, he has scored five goals and given four assists.
Clement Lenglet (Atletico)

The French centre back has donned the jerseys of Tottenham Hotspur, Aston Villa and FC Barcelona before finding his new home at the Spanish capital. He will need to marshal his team’s defence and ensure that Atletico clinch a clean sheet in the next game. He has so far played 10 games for Atletico in LaLiga 2025-26.
Match Facts
- In the last seven years, Betis won only once against Atletico.
- Luis Aragones is the leading goalscorer in this fixture.
- Atletico won the fixture in their last meeting.
Real Betis vs Atletico Madrid: Betting Tips and Odds
- Atletico to win the match – 11/10 with bet365
- Julian Alvarez to score a goal – 11/8 with bet365
- Real Betis 2-3 Atletico Madrid – 22/1 with bet365
Injury and Team News
The home side will miss the presence of Hector Bellerin, Junior Firpo and Sofyan Amrabat in the next game.
Antoine Griezmann, Alexander Sorloth and Marcos Llorente will be absent for the next game against Betis.
Head-to-Head
Total matches: 136
Betis won: 33
Atletico won: 73
Draws: 30
Predicted Lineups
Real Betis predicted lineup (4-3-3)
Valles (GK); Ruibal, Bartra, Llorente, Rodriguez; Roca, Deossa, Altimira; Antony, Avila, Ezzalazouli
Atletico predicted lineup (4-4-2)
Oblak (GK); Molina, Normand, Lenglet, Ruggeri; Koke, Barrios, Cardoso, Gonzalez; Almada, Alvarez
Match Prediction
Despite Atletico’s big list of absentees, we expect the away side to get the better of Real Betis narrowly in a closely contested fixture
Prediction: Real Betis 2-3 Atletico Madrid
Telecast Details
India: FanCode
UK: Premier Sports
Spain: RTVE
USA: ESPN+
When and where is the Real Betis vs Atletico Madrid game?
The match will take place on 6 February 2026, 1:30 am IST at Estadio La Cartuja.
Where to watch Copa del Rey in India?
The match can be viewed live on Fancode in India.
Where to watch Copa del Rey in the USA?
The match can be viewed live on ESPN in the USA.
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In addition to writing articles on World and Indian Football, Saikat has also covered tournaments like the Durand Cup, Indian Super League, and Hockey India League. Notably, his exceptional communication skills have seen him interview legendary icons like Olympic 2024 gold medalist Yibbi Jansen, former Real Madrid player Javi Hernandez, and many more such sporting stalwarts.