Jannik Sinner vs Alexei Popyrin prediction, betting tips & odds, head-to-head, preview: US Open 2025

The reigning champion takes on 2024 Canadian Open winner in the second round.

ATP World No. 1, Jannik Sinner, began his US Open title defence in dominant fashion, defeating Vit Kopriva 6-1, 6-1, 6-2 in just one hour and 40 minutes. The top seed dropped only four games, showcasing sharp form with five breaks of serve and winning 83% of his first-serve points.

The win marks Sinner’s 18th win at the US Open, tying Matteo Berrettini for the most by an Italian in the Open Era. He now faces Alexei Popyrin in the second round, looking to build on his confident start after retiring from the Cincinnati Open final earlier this month.

Feels great to be back here 👏🏻 Happy with today’s performance and grateful to be healthy again. Thank you all for the support ❤️ @usopen pic.twitter.com/Lo8oIMbGqo

— Jannik Sinner (@janniksin) August 26, 2025

Match details

• Tournament: US Open 2025 
• Round: Round 2
• Date: August 29
• Venue: USTA Billie Jean King National Tennis Center, New York
• Surface: Hard Court

Also Read: Five records Jannik Sinner can break at US Open 2025

Preview

Alexei Popyrin found himself ranked inside the top-20 ATP rankings for the major chunk of the 2025 season. However, his inability to retain the Toronto crown led to a huge dip in rankings for the Australian.

Having reached the fourth round in New York last year, more points are at stake for Popyrin as he faces a formidable challenge.

He outlasted Finland’s Emil Ruusuvuori in the opening round to set a date with World No. 1 Jannik Sinner. Popyrin had last year knocked out the defending champion Novak Djokovic and can never be underestimated.

Moreover, he holds the edge over the Italian on h2h, having emerged victorious in their only clash back in 2021 at Rome.

Form

• Jannik Sinner: W-L-W-W-W
• Alexei Popyrin: W-L-W-L-W

Head-to-head record

• Matches: 1
• Jannik Sinner: 0
• Alexei Popyrin: 1

Stats

Jannik Sinner

• Sinner has a 44-16 win-loss record in the 2025 season
• Sinner has a 18-5 win-loss record at the US Open
• Sinner has won 80% of the matches played on hard courts

Alexei Popyrin 

• Popyrin has a 16-19 win-loss record in the 2025 season
• Popyrin has a 9-5 win-loss record at the US Open
• Popyrin has won 57% of the matches played on hard courts

Also Read: US Open 2025: All you need to know about prize money & points on offer

Jannik Sinner vs Alexei Popyrin: Betting tips and odds

• Moneyline: Sinner -2500, Popyrin +1600
• Spread: Sinner -8.5 (+100), Popyrin +8.5 (-121)
• Total Games: Over 30.5 (-114), Under 30.5 (-114)
• 1st Set Winner: Sinner -700, Popyrin +460
• 1st Set Total Games: Over 9.5 (+138), Under 9.5 (-155)

Match prediction

Sinner is expected to reach the summit clash, but this will be a test. The Australian thrives during this particular hard-court swing, and produced some big upsets in Canada earlier, with victories over Holger Rune and Daniil Medvedev.

For Sinner, his first round was a mere warm-up. Should be completely fit and firing, Popyrin is unlikely to create much trouble. However, with this being only the second round and Sinner still finding his way into the competition, Popyrin could potentially dig deep into the Italian, if he serves and returns with consistency and accuracy.

Result: Jannik Sinner to win in four sets.

Where and how to watch live telecast and live streaming of Jannik Sinner vs Popyrin, second-round match at 2025 US Open?

Indian viewers can watch the US Open 2025 second-round clash between Jannik Sinner and Popyrin on the Star Sports network and streamed via JioHotstar.

UK fans can watch on Sky Sports Tennis, the Sky Sports+ app, or stream with a NOW TV Sports Pass. In the USA, coverage will be on ESPN platforms—ESPN2, ESPNEWS, and ESPN+ across all rounds.

For full worldwide broadcast details click here

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