Novak Djokovic vs Lorenzo Musetti prediction, betting tips & odds, head-to-head, preview: Miami Open 2025

Novak Djokovic is looking for his 100th career title.

Entering the Miami Open 2025, Novak Djokovic’s chances didn’t seem promising. However, the Serbian has once again silenced his critics, with two clinical victories so far. With his biggest rival, Carlos Alcaraz, out of the tournament, Djokovic has a golden opportunity to clinch his 100th career title and end his prolonged title drought.

Novak Djokovic holds the record for most titles by a male player, tied with Andre Agassi at six. With all to play for, the 37-year-old will be eager to capitalize on this favorable draw and add another milestone to his legendary career.

Also Read: Miami Open 2025: Updated schedule, fixtures, results, live streaming details

Match Details

• Tournament: Miami Open 2025 Men’s Singles
• Round: Fourth round
• Date: March 25
• Time: TBD
• Venue: Hard Rock Stadium, Miami, United States
• Surface: Hard

Preview

Djokovic scored a bagel against Rinky Hijikata in the first round and prevailed in a second-set tiebreak against Camilo Ugo Carabelli during the second-round encounter. Having prevented an upset and ended his three-match losing streak, the Serbian faces his first top-20 player challenge.

Lorenzo Musetti hasn’t had a great start to the new season but wins over in-form players like Felix Auger Aliassime and Quentin Halys, involving comebacks from being a set down, suggest he could be a force to reckon with.

Also Read: Miami Open 2025: All you need to know about prize money and points on offer

This pair has faced off eight times, with Djokovic dominating the head-to-head battle. Barring the 2023 ATP Masters 1000 Monte Carlo event, Djokovic has triumphed seven times over the Italian. Their most recent encounter came at the Paris Olympic Games, where the eventual gold medallist won in straight sets.

However, their last hard-court encounter was at the 2022 ATP Masters 1000 Paris, where the Serbian dominated with a commanding 6-0, 6-3 victory.

Form

• Novak Djokovic: W-W-L-L-L 
• Lorenzo Musetti: W-W-L-W-L

Head-to-head record

• Matches: 8
• Novak Djokovic: 7
• Lorenzo Musetti: 1

Also Read: Miami Open: Full list of title winners

Stats

Novak Djokovic

• Djokovic has an 8-4 win-loss record in the 2025 season.
• Djokovic has a 46-7 win-loss record in Miami.
• Djokovic has won 84% of matches played on hard courts.

Lorenzo Musetti

• Musetti has a 7-4 win-loss record in the 2025 season.
• Musetti has a 6-4 win-loss record in Miami.
• Musetti has won 48% of matches played on hard courts.

Novak Djokovic vs Lorenzo Musetti: Betting tips and odds

• Moneyline: Djokovic -300, Musetti +225.
• Spread: Djokovic -1.5 (-118), Musetti +1.5 (-120).
• Total games: Over 20.5 (-185), Under 20.5 (+125).

Match Prediction

Djokovic might not be in his best form, but things seem to be falling into place for the Serbian. Having last won an ATP title in 2023, the 24-time Grand Slam champion could potentially be on the verge of creating history in this edition of the Miami Open. Given his dominance over Musetti in recent years, including four victories in 2024 alone, Djokovic appears poised for another win, bringing him one step closer to his milestone 100th career title.

Also Read: Top five youngest men’s singles champions at Miami Open

Result: Djokovic will win in three sets.

Where and how to watch the live streaming and TV broadcast of the fourth-round match between Novak Djokovic vs Lorenzo Musetti at the Miami Open 2025?

Novak Djokovic and Lorenzo Musetti’s fourth-round match will be live telecast and streamed on Sony Network in India. Sky UK is the official broadcaster in the United Kingdom, while the Tennis Channel fulfills that role within the United States. 

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